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Jonathan L Sessler Selected Research

texaphyrin

1/2020Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents.
12/2016Liposomal Texaphyrin Theranostics for Metastatic Liver Cancer.
11/2013Recent developments in texaphyrin chemistry and drug discovery.
1/2012A texaphyrin-oxaliplatin conjugate that overcomes both pharmacologic and molecular mechanisms of cisplatin resistance in cancer cells.
3/2011Overcoming biochemical pharmacologic mechanisms of platinum resistance with a texaphyrin-platinum conjugate.
5/2004Biodistribution assessment of a lutetium(III) texaphyrin analogue in tumor-bearing mice using NIR Fourier-transform Raman spectroscopy.

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Jonathan L Sessler Research Topics

Disease

44Neoplasms (Cancer)
08/2022 - 05/2004
6Hypoxia (Hypoxemia)
01/2021 - 07/2008
2Neoplasm Metastasis (Metastasis)
08/2022 - 02/2019
2Lung Neoplasms (Lung Cancer)
06/2021 - 07/2008
2Neurodegenerative Diseases (Neurodegenerative Disease)
05/2020 - 03/2020
2Alzheimer Disease (Alzheimer's Disease)
03/2020 - 01/2019
2Prostatic Neoplasms (Prostate Cancer)
06/2019 - 07/2008
2Carcinoma (Carcinomatosis)
01/2016 - 09/2005
2Hyperthermia
11/2013 - 12/2012
1Reperfusion Injury
12/2022
1Chemical and Drug Induced Liver Injury
12/2022
1Thrombosis (Thrombus)
01/2022
1Breast Neoplasms (Breast Cancer)
01/2021
1Iron Overload
01/2021
1Disease Progression
10/2020
1Ischemic Stroke
01/2020
1Colonic Neoplasms (Colon Cancer)
10/2019
1Death (Near-Death Experience)
09/2018

Drug/Important Bio-Agent (IBA)

8Pharmaceutical PreparationsIBA
04/2021 - 03/2011
7ProdrugsIBA
08/2022 - 08/2012
6PlatinumIBA
07/2020 - 12/2009
6texaphyrinIBA
01/2020 - 05/2004
5PorphyrinsIBA
07/2020 - 01/2007
5MetalsIBA
06/2020 - 07/2008
4IronIBA
08/2022 - 06/2020
4Cisplatin (Platino)FDA LinkGeneric
06/2022 - 03/2011
4Photosensitizing Agents (Photosensitizers)IBA
01/2021 - 05/2004
4Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 12/2012
3Chelating AgentsIBA
06/2021 - 06/2020
3Folic Acid (Vitamin M)FDA LinkGeneric
01/2021 - 11/2015
31-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2021 - 02/2002
34,4- difluoro- 4- bora- 3a,4a- diaza- s- indacene (BODIPY)IBA
01/2021 - 01/2017
3Contrast MediaIBA
01/2020 - 08/2013
3EnzymesIBA
01/2018 - 01/2014
3LigandsIBA
01/2018 - 08/2013
3Antineoplastic Agents (Antineoplastics)IBA
06/2017 - 11/2006
3motexafin gadoliniumIBA
11/2013 - 09/2005
2Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2019
2DeferasiroxFDA Link
06/2021 - 01/2021
2ThioredoxinsIBA
04/2021 - 11/2015
2Acetazolamide (Diamox)FDA LinkGeneric
01/2021 - 01/2017
2Oxygen (Dioxygen)IBA
01/2021 - 02/2019
2Fluorescent Dyes (Fluorescent Probes)IBA
01/2021 - 08/2020
2IonophoresIBA
06/2020 - 07/2008
2ZincIBA
06/2020 - 07/2008
2AntioxidantsIBA
03/2020 - 01/2020
2Irinotecan (Camptosar)FDA LinkGeneric
10/2019 - 04/2014
2Sulfhydryl Compounds (Thiols)IBA
01/2018 - 11/2015
2Oxaliplatin (Eloxatin)FDA LinkGeneric
06/2017 - 01/2012
2Glutathione (Reduced Glutathione)IBA
12/2016 - 11/2015
2Biotin (Vitamin H)FDA Link
01/2016 - 11/2015
2DisulfidesIBA
11/2015 - 08/2012
2arginyl-glycyl-aspartic acidIBA
11/2015 - 08/2012
2Biological ProductsIBA
02/2011 - 01/2007
2PCI 2050IBA
01/2007 - 11/2006
2sapphyrinIBA
01/2007 - 11/2006
1Peroxynitrous Acid (Peroxynitrite)IBA
12/2022
1Adenosine Triphosphate (ATP)IBA
12/2022
1MXeneIBA
08/2022
1PhytochromeIBA
01/2022
1Superoxides (Superoxide)IBA
01/2022
11,2-distearoylphosphatidylethanolamine (DSPE)IBA
01/2022
1Human Serum AlbuminFDA LinkGeneric
04/2021
1Blood Proteins (Serum Proteins)IBA
04/2021
13,4-difluorobenzylidenecurcuminIBA
01/2021
1NitroreductasesIBA
01/2021
1Ethacrynic Acid (Etacrynic Acid)FDA Link
01/2021
1Amyloid beta-PeptidesIBA
10/2020
1Hemin (Panhematin)FDA Link
10/2020
1porphyceneIBA
07/2020
1CopperIBA
06/2020
1Mitochondrial DNA (mtDNA)IBA
06/2020
1Anti-Bacterial Agents (Antibiotics)IBA
06/2020
1Ciprofloxacin (Cipro)FDA LinkGeneric
06/2020
1Radioisotopes (Radionuclides)IBA
03/2020
1PyrrolesIBA
02/2020
1CatalaseIBA
01/2020
1disalicylaldehyde ethylenediamine (salen)IBA
01/2020
1Neuroprotective AgentsIBA
01/2020
1ManganeseIBA
01/2020
1GadoliniumIBA
01/2020
1Crown Ethers (Ethers, Crown)IBA
01/2020
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2019
1Dimethyl Sulfoxide (DMSO)FDA LinkGeneric
10/2019
1AnionsIBA
08/2019
1diketopyrrolopyrrole dyeIBA
06/2019
1Cholinergic Agents (Cholinergics)IBA
01/2019
1quinone (benzoquinone)IBA
01/2019
1Donepezil (Aricept)FDA LinkGeneric
01/2019
1NAD (NADH)IBA
01/2019
1Biomarkers (Surrogate Marker)IBA
01/2019
1AcetylcholinesteraseIBA
01/2019
1LithiumIBA
09/2018
1SaltsIBA
09/2018

Therapy/Procedure

6Therapeutics
08/2022 - 04/2014
5Drug Therapy (Chemotherapy)
08/2022 - 02/2011
5Photochemotherapy (Photodynamic Therapy)
01/2021 - 02/2002
4Precision Medicine
01/2018 - 04/2014
1Immunotherapy
01/2022
1Photothermal Therapy
04/2018